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NCT02422979 (Clinical Trial / DFRF4539A / RG-7598)

Study Title
A Study of DFRF4539A in Patients With Relapsed or Refractory Multiple Myeloma (NCT02422979)

Trial Description
This multicenter, open-label, dose-escalating study will assess the safety and efficacy of the antibody-drug conjugate DFRF4539A (RG-7598) in patients with relapsed or refractory multiple myeloma. Cohorts of patients will receive multiple ascending doses of intravenous DFRF4539A every 3 weeks or weekly. Patients exhibiting acceptable safety and evidence of clinical benefit may receive DFRF4539A for up to 17 cycles. Anticipated time on study treatment is 1 year or until disease progression or unacceptable toxicity occurs.

This trial is sponsored by Genentech. [1]

Study Data

  • Condition: Multiple Myeloma
  • Interventions:
    • Drugs used in this trial
      • DFRF4539A (RG-7598)
  • Phase: I
  • Enrollment: 39
  • Start: September 2011
  • Completion: April 2014
  • Last verified: July 2015

Study Schematic

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Last Editorial review: July 14, 2015
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.

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