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NCT01786096 (Clinical Trial / Denintuzumab mafodotin / SGN-CD19A / SGN-19A / hBU12-491)

Study Title
A Safety Study of SGN-CD19A for Leukemia and Lymphoma (NCT01786096)

Trial Description
This is a phase I, open-label, dose-escalation, multicenter study to evaluate the safety and tolerability of SGN-CD19A (also known as denintuzumab mafodotin/ SGN-CD19A/ hBU12-491) in adult and pediatric patients with relapsed or refractory B-lineage acute lymphoblastic leukemia (B-ALL), Burkitt lymphoma or leukemia, or B-lineage lymphoblastic lymphoma (B-LBL).

This trial is sponsored by Seattle Genetics. [1]

Study Data

  • Condition: Leukemia and Lymphoma
  • Interventions:
    • Drugs used in this trial
      • SGN-CD19A  (denintuzumab mafodotin; SGN-CD19A; hBU12-491)
  • Phase: I
  • Estimated Enrollment: 92
  • Start: February 2013
  • Estimated Completion: June 2016
  • Last verified: March 2016

Study Schematic 

NCT01786096 (CLINICAL TRIAL / DENINTUZUMAB MAFODOTIN / SGN-CD19A / SGN-19A / HBU12-491)


Last Editorial review: July 29, 2016
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.

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