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NCT01290549 (Clinical Trial / DCDS4501A / Polatuzumab Vedotin / RG-7596)

Study Title
A Study of Escalating Doses of DCDS4501A in Patients With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma and Chronic Lymphocytic Leukemia and DCDS4501A in Combination With Rituximab in Patients With Relapsed or Refractory B-Cell Non-Hodgkins Lymphoma (NCT01290549)

Trial Description
This is a Phase I, multicenter, open-label, dose-escalation study of DCDS4501A (also known as polatuzumab vedotin or RG-7596) administered as a single agent by IV infusion to patients with relapsed or refractory hematologic malignancies. In Phase Ib, patients will receive DCDS4501A in combination with rituximab.

This trial is sponsored by Genentech.

Study Data

  • Conditions:
    • Non-Hodgkin’s Lymphoma
    • Chronic Lymphocytic Leukemia
  • Interventions:
    • Drugs used in this trial
  • Phase: I
  • Enrollment: 95
  • Start: March 2011
  • Primary Completion: June 2012
  • Last verified: February 2015

Study Schematic

(Coming soon)

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Last Editorial review: July 13, 2015
Information based on (NIH/NCI) and other sources.

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