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NCT01232556 (Clinical Trial / inotuzumab ozogamycin / CMC-544)

Study Title
A Study Of Inotuzumab Ozogamicin Plus Rituximab For Relapsed/Refractory Aggressive Non-Hodgkin Lymphoma Patients Who Are Not Candidates For Intensive High-Dose Chemotherapy (NCT01232556)

Trial Description
The purpose of this study is to evaluate the efficacy of inotuzumab ozogamicin (also known as CMC-544) plus rituximab in relapsed/refractory aggressive Non-Hodgkin lymphoma patients who are not candidates for intensive high-dose chemotherapy. Specifically, the goal is to demonstrate the superiority of this combination compared with an active comparator arm (investigator’s choice of rituximab+bendamustine or rituximab+gemcitabine) using the primary endpoint of overall survival.

This trial is sponsored by UCB Pharma/ Pfitzer. [1]

Study Data

Study Schematic 

NCT01232556 (Clinical Trial / inotuzumab ozogamycin / CMC-544)

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Last Editorial review: July 31, 2016
Information based on ClinicalTrials.gov (NIH/NCI) and other sources.

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